This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

製品の概要

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    ab77417 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunising peptide.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

  • 追加情報
    Peptide ELISA: Antibody detection limit dilution 1/4000.
    WB: Preliminary experiments in Human Brain (Amygdala, Cerebellum, Cerebral Cortex, Frontal Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). Predicted molecular weight: 46 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
    • 細胞内局在
      Golgi apparatus membrane; Multipass membrane protein.
    • 参照データベース
    • 別名
      • BC056494 antibody
      • E3 ubiquitin protein ligase MARCH4 antibody
      • KIAA1399 antibody
      • MARCH 4 antibody
      • MARCH IV antibody
      • Membrane associated RING CH protein IV antibody
      • Membrane associated ring finger (C3HC4) 4 antibody
      • Membrane associated RING finger protein 4 antibody
      • MGC104908 antibody
      • mKIAA1399 antibody
      • RING finger protein 174 antibody
      • RNF174 antibody
      see all

    参考文献

    ab77417 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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