製品の概要

  • 製品名Anti-MAP3K8 antibody [EP1103Y]
    MAP3K8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP1103Y] to MAP3K8
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC/IF,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide (Human)

  • ポジティブ・コントロール
    • Jurkat cell lysate
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab52613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Predicted molecular weight: 53 kDa.
  • 追加情報Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • ターゲット情報

    • 機能Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle. The longer form has some transforming activity, although it is much weaker than the activated cot oncoprotein.
    • 組織特異性Expressed in several normal tissues and human tumor-derived cell lines.
    • 配列類似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • 発生段階Isoform 1 is activated specifically during the S and G2/M phases of the cell cycle.
    • 翻訳後修飾Autophosphorylated. Isoform 1 undergoes phosphorylation mainly on Ser residues, and isoform 2 on both Ser and Thr residues.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • c COT antibody
      • Cancer Osaka thyroid oncogene antibody
      • CCOT antibody
      • COT antibody
      • COT proto oncogene serine/threonine protein kinase antibody
      • EST antibody
      • ESTF antibody
      • Ewing sarcoma transformant antibody
      • FLJ10486 antibody
      • M3K8_HUMAN antibody
      • MAP3K 8 antibody
      • MAP3K8 antibody
      • MEKK8 antibody
      • Mitogen activated protein kinase kinase kinase 8 antibody
      • Mitogen-activated protein kinase kinase kinase 8 antibody
      • Proto oncogene cCot antibody
      • Proto-oncogene c-Cot antibody
      • Serine/threonine protein kinase cot antibody
      • Serine/threonine-protein kinase cot antibody
      • TPL 2 antibody
      • TPL-2 antibody
      • TPL2 antibody
      • Tumor progression locus 2 antibody
      see all

    Anti-MAP3K8 antibody [EP1103Y] 画像

    • Anti-MAP3K8 antibody [EP1103Y] (ab52613) at 1/500 dilution + Jurkat cell lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP antibody at 1/2000 dilution

      Predicted band size : 53 kDa
      Observed band size : 53 kDa

    Anti-MAP3K8 antibody [EP1103Y] (ab52613) 使用論文

    ab52613 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab52613.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"