製品の概要

  • 製品名Anti-MAP1S antibody
    MAP1S 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to MAP1S
  • アプリケーション適用あり: WB, ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 929-1027 of Human MAP1S with a proprietary tag (NP_060644).

  • ポジティブ・コントロール
    • Recombinant Protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa

アプリケーション

Our Abpromise guarantee covers the use of ab118111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 112 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.
  • 組織特異性Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle.
  • 配列類似性Belongs to the MAP1 family.
  • ドメインThe N-terminus of the heavy chain associates with the C-terminus of the light chain to form the heterodimer complex (By similarity). Its C-terminal part of the heavy chain interacts with ESR1.
  • 細胞内局在Nucleus. Cytoplasm > cytosol. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > spindle. Detected in filopodia-like protrusions and synapses (By similarity). Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BPY2-interacting protein 1 antibody
    • BPY2IP1 antibody
    • C19orf5 antibody
    • FLJ10669 antibody
    • MAP-1S antibody
    • MAP1S antibody
    • MAP1S light chain antibody
    • MAP1S_HUMAN antibody
    • MAP8 antibody
    • MGC133087 antibody
    • microtubule-associated protein 1S antibody
    • Microtubule-associated protein 8 antibody
    • Variable charge Y chromosome 2-interacting protein 1 antibody
    • VCY2-interacting protein 1 antibody
    • VCY2IP-1 antibody
    • VCY2IP1 antibody
    see all

Anti-MAP1S antibody 画像

  • Anti-MAP1S antibody (ab118111) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 112 kDa
  • ab118111 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged MAP1S is 0.1 ng/ml.

Anti-MAP1S antibody (ab118111) 使用論文

ab118111 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"