製品の概要

  • 製品名Anti-MAP1LC3A antibody
    MAP1LC3A 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to MAP1LC3A
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Pig
  • 免疫原

    Synthetic peptide:

    DIYEQEKDED

    with a Cysteine residue linker, corresponding to internal sequence amino acids 97-106 of Human MAP1LC3A (NP_115903.1).

  • ポジティブ・コントロール
    • Human Brain Cerebellum and cortex and Human Liver tissues.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3.75 - 7.5 µg/ml.

ターゲット情報

  • 機能Probably involved in formation of autophagosomal vacuoles (autophagosomes).
  • 組織特異性Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
  • 配列類似性Belongs to the MAP1 LC3 family.
  • 翻訳後修飾The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
  • 細胞内局在Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ATG8E antibody
    • Autophagy-related protein LC3 A antibody
    • Autophagy-related ubiquitin-like modifier LC3 A antibody
    • LC3 antibody
    • LC3A antibody
    • MAP1 light chain 3 like protein 1 antibody
    • MAP1 light chain 3-like protein 1 antibody
    • MAP1A/1B light chain 3 A antibody
    • MAP1A/MAP1B LC3 A antibody
    • MAP1A/MAP1B light chain 3 A antibody
    • MAP1ALC3 antibody
    • MAP1BLC3 antibody
    • Map1lc3a antibody
    • Microtubule associated proteins 1A/1B light chain 3 antibody
    • Microtubule-associated protein 1 light chain 3 alpha antibody
    • Microtubule-associated proteins 1A and 1B, light chain 3 antibody
    • Microtubule-associated proteins 1A/1B light chain 3A antibody
    • MLP3A_HUMAN antibody
    see all

Anti-MAP1LC3A antibody 画像

  • ab118493 at 7.5 µg/ml staining MAP1LC3A in Formalin-fixed, Paraffin-embedded Human Brain cerebellum tissue by Immunohistochemistry.
  • ab118493 at 7.5 µg/ml staining MAP1LC3A in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
  • ab118493 at 7.5 µg/ml staining MAP1LC3A in Formalin-fixed, Paraffin-embedded Human Liver cerebellum tissue by Immunohistochemistry.

Anti-MAP1LC3A antibody (ab118493) 使用論文

ab118493 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"