Anti-MAP 2a + 2b + 2c 抗体 [0.N.395] (ab33580)

製品の概要

  • 製品名Anti-MAP 2a + 2b + 2c antibody [0.N.395]
    MAP 2a + 2b + 2c 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [0.N.395] to MAP 2a + 2b + 2c
  • 特異性Ab33580 is highly specific to MAP 2a, b and c expressed in dendrites and cell bodies of neurons. It recognizes MAP2a and MAP2b (~280kD doublet) and MAP2c (70kD). It shows no crossreactivity with other MAPs, tau and tubulin.
  • アプリケーション適用あり: IHC-P, IHC-FoFr, WB, ICC/IFmore details
  • 種交差性
    交差種: Rat, Cow, Human, Xenopus laevis, Quail
  • 免疫原

    Full length native protein: Bovine brain MAP2.

  • エピトープAb33580 reacts with an epitope located in in the first 151 amino acids of MAP2.
  • ポジティブ・コントロール
    • IMR5 or T98G human glioblastoma cells or brain.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab33580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IHC-FoFr Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval before commencing the IHC protocol.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 199 kDa.
ICC/IF Use at an assay dependent concentration.

ターゲット情報

  • 機能The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
  • 配列類似性Contains 3 Tau/MAP repeats.
  • 翻訳後修飾Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. Isoform MAP2c is phosphorylated by FYN at Tyr-67.
  • 細胞内局在Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MAP 2 antibody
    • MAP-2 antibody
    • MAP2 antibody
    • MAP2_HUMAN antibody
    • MAP2A antibody
    • MAP2B antibody
    • MAP2C antibody
    • MAP2R antibody
    • Microtubule associated protein 2 antibody
    • Microtubule-associated protein 2 antibody
    • Mtap2 antibody
    see all

Anti-MAP 2a + 2b + 2c antibody [0.N.395] (ab33580) 使用論文

ab33580 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"