Anti-Malondialdehyde 抗体 (FITC) (ab27615)

製品の概要

  • 製品名
    Anti-Malondialdehyde antibody (FITC)
    Malondialdehyde 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Malondialdehyde (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • 特異性
    This antibody specifically binds to Malondialdehyde.
  • アプリケーション
    適用あり: ICC/IFmore details
  • 免疫原

    Chemical/ Small Molecule MDA modified protein

  • 特記事項

    Molar FITC/ Protein ratio is 3.1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab27615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution.

ターゲット情報

  • 関連性
    Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts.
  • 別名
    • 1133 Tetramethoxypropane antibody
    • MDA antibody

参考文献

ab27615 has not yet been referenced specifically in any publications.

レビューと Q&A

Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 21°C
Antigen retrieval step
None
Sample
Rat Tissue sections (Rat Forebrain)
Specification
Rat Forebrain
Permeabilization
No
Fixative
Paraformaldehyde
Username

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投稿 Oct 23 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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