FITC Anti-Malondialdehyde 抗体 (ab27615)
Key features and details
- FITC Goat polyclonal to Malondialdehyde
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
製品の概要
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製品名
FITC Anti-Malondialdehyde antibody
Malondialdehyde 一次抗体 製品一覧 -
製品の詳細
FITC Goat polyclonal to Malondialdehyde -
由来種
Goat -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
This antibody specifically binds to Malondialdehyde. -
免疫原
Chemical/ Small Molecule MDA modified protein
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特記事項
Molar FITC/ Protein ratio is 3.1
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 6.5
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0146% EDTA, 0.435% Sodium chloride, 0.5% BSA, 30% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified by Malondialdehyde modified protein-Sepharose™ affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
ターゲット情報
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関連性
Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts. -
別名
- 1133 Tetramethoxypropane antibody
- MDA antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab27615 は論文での使用が確認できていません。