製品の概要

  • 製品名Anti-MAdCAM1 antibody
    MAdCAM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to MAdCAM1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 235-284 (TTSPESPDTT SPESPDTTSQ EPPDTTSPEP PDKTSPEPAP QQGSTHTPRS) of Human MAdCAM1 (NP_570116).

  • ポジティブ・コントロール
    • MDA-MB-435S cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 40 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
  • 組織特異性Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes.
  • 配列類似性Contains 2 Ig-like (immunoglobulin-like) domains.
  • 翻訳後修飾The Ser/Thr-rich mucin-like domain may provide possible sites for O-glycosylation.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Addressin mucosal antibody
    • hMAdCAM 1 antibody
    • hMAdCAM-1 antibody
    • MACAM1 antibody
    • MADCA_HUMAN antibody
    • MAdCAM 1 antibody
    • MAdCAM-1 antibody
    • Madcam1 antibody
    • Mucosal addressin cell adhesion molecule 1 antibody
    • Mucosal vascular addressin cell adhesion molecule 1 antibody
    see all

Anti-MAdCAM1 antibody 画像

Anti-MAdCAM1 antibody (ab125397) 使用論文

ab125397 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab125397.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"