Anti-Macrophage Inflammatory Protein 3 alpha 抗体 (ab25123)
Key features and details
- Rabbit polyclonal to Macrophage Inflammatory Protein 3 alpha
- Suitable for: WB
- Isotype: IgG
製品の概要
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製品名
Anti-Macrophage Inflammatory Protein 3 alpha antibody
Macrophage Inflammatory Protein 3 alpha 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Macrophage Inflammatory Protein 3 alpha -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
免疫原
E.coli expressed recombinant fragment: MACKHLPFLA LAGVLLAYL CSQSEAASN FDCCLTYTK NVYHHARNF VGFTTQMAD EACDINAII, corresponding to N terminal amino acids 1-70 of Rat Macrophage Inflammatory Protein 3 alpha
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 99.9% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25123の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/2000. Predicted molecular weight: 11 kDa.
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特記事項 |
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WB
1/2000. Predicted molecular weight: 11 kDa. |
ターゲット情報
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機能
Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. -
組織特異性
Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon. -
配列類似性
Belongs to the intercrine beta (chemokine CC) family. -
翻訳後修飾
C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
細胞内局在
Secreted. - Information by UniProt
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別名
- Beta chemokine exodus 1 antibody
- Beta-chemokine exodus-1 antibody
- C C motif chemokine ligand 20 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab25123 は 2 報の論文で使用されています。
- Krebs R et al. Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis. Am J Pathol 181:1607-20 (2012). PubMed: 22959907
- Qi W et al. High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism. Nephrol Dial Transplant 22:3147-53 (2007). PubMed: 17664181