Anti-Macrophage Inflammatory Protein 1 beta 抗体 (ab10384)

製品の概要

  • 製品名Anti-Macrophage Inflammatory Protein 1 beta antibody
    Macrophage Inflammatory Protein 1 beta 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Macrophage Inflammatory Protein 1 beta
  • 特異性Human MIP1 beta neutralizes the of bioactivity of recombinant, human MIP1 beta, but not that of recombinant, mouse MIP1 beta, recombinant, human MIP1 alpha or recombinant, mouse MIP1 beta. In indirect ELISA and immunoblotting, this antibody displays approximately 8% cross-reactivity with recombinant, mouse MIP1 alpha, recombinant, human MIP1 alpha and recombinant, mouse MIP1 beta. The product shows no cross-reactivity with other tested cytokines using indirect ELISA.
  • アプリケーション適用あり: ELISA, WB, Neutralisingmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant, human macrophage inflammatory protein 1 beta expressed in Sf 21 insect cells.

  • 特記事項

    Endotoxin: <10 ng/vial.

    This product was lyopholized in PBS with trehalose.

     

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab10384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
Neutralising
  • 追加情報ELISA: Use at a concentration of 0.125 µg/ml to detect 1ng/well of recombinant human MIP1 beta.
    Neut: Use at a concentration of 30 µg/ml.
    WB: Use at a concentration of 1 µg/ml to detect 2ng/lane of recombinant human MIP1 beta under non-reducing conditions. Predicted molecular weight: 11 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
    • 配列類似性Belongs to the intercrine beta (chemokine CC) family.
    • 翻訳後修飾N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • MIP 1 beta antibody
      • Secreted protein G 26 antibody
      • ACT 2 antibody
      • ACT-2 antibody
      • ACT2 antibody
      • AT744.1 antibody
      • AT744.2 antibody
      • C C motif chemokine 4 antibody
      • C C motif chemokine 4 like antibody
      • C C motif chemokine ligand 4 like 1 antibody
      • CC chemokine ligand 4 antibody
      • CC chemokine ligand 4L1 antibody
      • CC chemokine ligand 4L1d2 antibody
      • CC chemokine ligand 4L2 antibody
      • CCL4 antibody
      • CCL4_HUMAN antibody
      • ccl4l 1 antibody
      • CCL4L antibody
      • CCL4L1 antibody
      • Chemokine (C C motif) ligand 4 antibody
      • Chemokine (C C motif) ligand 4 like 1 antibody
      • Chemokine (C C motif) ligand 4 like 1, telomeric antibody
      • Chemokine (C C motif) ligand 4 like 2 antibody
      • Chemokine CC Motif Ligand 4 antibody
      • G 26 antibody
      • G 26 T lymphocyte secreted protein antibody
      • G-26 T-lymphocyte-secreted protein antibody
      • HC21 antibody
      • Immune activation 2 antibody
      • LAG 1 antibody
      • LAG-1 antibody
      • LAG1 antibody
      • Lymphocyte activation gene 1 antibody
      • Lymphocyte activation gene 1 protein antibody
      • Macrophage inflammatory protein 1 beta antibody
      • Macrophage inflammatory protein 1-beta antibody
      • Macrophage inflammatory protein 1b2 antibody
      • MGC104418 antibody
      • MGC126025 antibody
      • MGC126026 antibody
      • MIP-1-beta antibody
      • MIP-1-beta(1-69) antibody
      • MIP-1-beta(3-69) antibody
      • MIP1 beta antibody
      • MIP1B antibody
      • MIP1B1 antibody
      • Monocyte adherence induced protein 5 alpha antibody
      • PAT 744 antibody
      • Protein H400 antibody
      • SCYA2 antibody
      • SCYA4 antibody
      • SCYA4L antibody
      • SCYA4L1 antibody
      • SCYQ4L2 antibody
      • Secreted protein G 26 antibody
      • Secreted protein G26 antibody
      • SIS gamma antibody
      • SIS-gamma antibody
      • Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody
      • Small inducible cytokine A4 antibody
      • small inducible cytokine A4-like antibody
      • Small-inducible cytokine A4 antibody
      • T cell activation protein 2 antibody
      • T-cell activation protein 2 antibody
      see all

    Anti-Macrophage Inflammatory Protein 1 beta antibody (ab10384) 使用論文

    This product has been referenced in:
    • Schmidt J  et al. Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. Brain 131:1228-40 (2008). IHC-P ; Human . Read more (PubMed: 18420712) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab10384.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"