製品の概要

  • 製品名Anti-Macrophage antibody [5/9]
    Macrophage 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [5/9] to Macrophage
  • アプリケーション適用あり: IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A cell suspension containing osteoclasts from osteoclastomas (Human).

  • 特記事項


    This antibody may be used as a macrophage cell marker, and may be useful for the identification of osteoclasts in tissues to study developmental pathobiology.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度IgG fraction
  • 一次抗体 備考This antibody may be used as a macrophage cell marker, and may be useful for the identification of osteoclasts in tissues to study developmental pathobiology.
  • ポリ/モノモノクローナル
  • クローン名5/9
  • ミエローマP3x63-Ag8.653
  • アイソタイプIgG1
  • 軽鎖の種類unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab20214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 関連性Macrophages comprise of many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and promonocyte states of the monocyte stage, they enter the blood, where they circulate for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content becomming macrophages. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, killing of ingested microorganisms, digestion and presentation of antigens to T and B lymphocytes, and secretion of a large number of diverse products, including many enzymes including lysozyme and collagenases, several complement components and coagulation factors, some prostaglandins and leukotrienes, and many regulatory molecules (Interferon, Interleukin 1). Among cells that are now recognised as macrophages are histiocytes, Kupffer cells, osteoclasts, microglial cells, synovial type A cells, interdigitating cells, and Langerhans cells (in normal tissues) and epithelioid cells and Langerhans-type and foreign-body-type multinucleated giant cells (in inflamed tissues).
  • 別名
    • macrophages antibody

Anti-Macrophage antibody [5/9] (ab20214) 使用論文

This product has been referenced in:
  • Horton MA  et al. Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer Res 45:5663-9 (1985). Read more (PubMed: 4053038) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"