製品の概要

  • 製品名
    Anti-LZTS2 antibody
  • 製品の詳細
    Rabbit polyclonal to LZTS2
  • 特異性
    This antibody is predicted to not cross-react with other LZTS family members.
  • アプリケーション
    適用あり: WB, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to 19 amino acids near the N-terminus of Human LZTS2 (NP_115805).

  • ポジティブ・コントロール
    • Human kidney tissue lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG

アプリケーション

Our Abpromise guarantee covers the use of ab124191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 73 kDa.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
  • 組織特異性
    Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.
  • 配列類似性
    Belongs to the LZTS2 family.
  • 細胞内局在
    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hLZTS2 antibody
    • KIAA1813 antibody
    • LAPSER1 antibody
    • Leucine zipper putative tumor suppressor 2 antibody
    • LZTS2 antibody
    • LZTS2_HUMAN antibody
    • OTTHUMP00000020289 antibody
    • Protein LAPSER1 antibody
    • RP11-108L7.8 antibody
    see all

画像

  • Immunofluorescence of LZTS2 in Human kidney tissue with ab124191 at 20 ug/mL.
  • Immunohistochemistry of LZTS2 in Human kidney tissue with ab124191 at 2.5 μg/mL.

  • Anti-LZTS2 antibody (ab124191) at 1 µg/ml + Human kidney tissue lysate at 15 µg

    Predicted band size : 73 kDa

参考文献

ab124191 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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