製品の概要

  • 製品名Anti-LY75 antibody [RC38]
    LY75 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [RC38] to LY75
  • 特異性RC38 stains over 95% of primary renal cell carcinomas and 60% of metastases of renal cell carcinoma and glomerular visceral epithelium and proximal tubules in normal kidney (cytoplasmic). It does not stain epithelial cells of non renal malignancies.
  • アプリケーション適用あり: IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A mouse was immunized with renal cell carcinoma homogenate. After fusing the spleen cells from this mouse with myeloma cells, antibody producing cells were screened on thin sections of various human tissues.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: PBS
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名RC38
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab2489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr
  • 追加情報IHC-Fr: Use at an assay dependent concentration.
    Supernatant: for frozen tissue sections it can be diluted 1:20 in PBS/1%BSA.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
    • 組織特異性Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
    • 配列類似性Contains 10 C-type lectin domains.
      Contains 1 fibronectin type-II domain.
      Contains 1 ricin B-type lectin domain.
    • 翻訳後修飾N-glycosylated.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C-type lectin domain family 13 member B antibody
      • CD 205 antibody
      • CD205 antibody
      • CD205 antigen antibody
      • CLEC 13B antibody
      • CLEC13B antibody
      • DEC 205 antibody
      • DEC-205 antibody
      • DEC205 antibody
      • gp200 antibody
      • gp200 MR6 antibody
      • gp200-MR6 antibody
      • LY 75 antibody
      • Ly-75 antibody
      • LY75 antibody
      • LY75_HUMAN antibody
      • Lymphocyte antigen 75 antibody
      • Renal Cell Carcinoma (gp200) antibody
      see all

    Anti-LY75 antibody [RC38] 画像

    • ab2489 staining human renal cell carcinoma by Immunohistochemistry (frozen sections).

    Anti-LY75 antibody [RC38] (ab2489) 使用論文

    ab2489 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab2489.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"