製品の概要

  • 製品名Anti-LY75 antibody [PN-15] (Biotin)
    LY75 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [PN-15] to LY75 (Biotin)
  • 標識Biotin
  • 特異性ab79458 shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens.
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Microsomal fraction of human renal cortical tissue homogenate

  • ポジティブ・コントロール
    • Normal kidney. Renal cell carcinoma tissue.
  • 特記事項


    ab79458 may be a useful reagent in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.2% BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 一次抗体 備考ab79458 may be a useful reagent in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
  • ポリ/モノモノクローナル
  • クローン名PN-15
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab79458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 198 kDa.
IHC-P Use a concentration of 2 - 4 µg/ml.

Use for 30 min at RT. Staining of formalin-fixed tissues requires digestion with Protease XXV at 1mg/ml PBS for 10 minutes at 37°C.

ターゲット情報

  • 機能Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
  • 組織特異性Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
  • 配列類似性Contains 10 C-type lectin domains.
    Contains 1 fibronectin type-II domain.
    Contains 1 ricin B-type lectin domain.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-type lectin domain family 13 member B antibody
    • CD 205 antibody
    • CD205 antibody
    • CD205 antigen antibody
    • CLEC 13B antibody
    • CLEC13B antibody
    • DEC 205 antibody
    • DEC-205 antibody
    • DEC205 antibody
    • gp200 antibody
    • gp200 MR6 antibody
    • gp200-MR6 antibody
    • LY 75 antibody
    • Ly-75 antibody
    • LY75 antibody
    • LY75_HUMAN antibody
    • Lymphocyte antigen 75 antibody
    • Renal Cell Carcinoma (gp200) antibody
    see all

Anti-LY75 antibody [PN-15] (Biotin) (ab79458) 使用論文

This product has been referenced in:
  • Yoshida SO & Imam A Monoclonal antibody to a proximal nephrogenic renal antigen: immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas. Cancer Res 49:1802-9 (1989). Read more (PubMed: 2466563) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"