製品の概要

  • 製品名
    Anti-LY75 antibody [NLDC-145] (Biotin)
    LY75 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [NLDC-145] to LY75 (Biotin)
  • 標識
    Biotin
  • 特異性
    Reacts with Mouse non lymphoid dendritic cells: interdigitating cells (IDC), veiled cells and Langerhans cells, thymic epithelial cells.
  • アプリケーション
    適用あり: Flow Cyt, IHC-Frmore details
    適用なし: IHC-P
  • 種交差性
    交差種: Mouse
  • 免疫原

    Mouse lymph node tissue

  • エピトープ
    The antigen is a protein of 205kDa molecular weight which is localized on the cell surface and intracellularly. The epitope has not been further characterized.
  • ポジティブ・コントロール
    • The following tissues also tested positive: Lymph node, Peyer’s patch, Thymus and Skin.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, 5mg/ml BSA, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    NLDC-145
  • アイソタイプ
    IgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab51820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IHC-Fr
  • 追加情報
    Flow Cyt: Use at an assay dependent dilution (PMID 19109143).
    IHC-Fr: Use at a concentration of 3 µg/ml.


    Is unsuitable for IHC-P.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
    • 組織特異性
      Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
    • 配列類似性
      Contains 10 C-type lectin domains.
      Contains 1 fibronectin type-II domain.
      Contains 1 ricin B-type lectin domain.
    • 翻訳後修飾
      N-glycosylated.
    • 細胞内局在
      Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C-type lectin domain family 13 member B antibody
      • CD 205 antibody
      • CD205 antibody
      • CD205 antigen antibody
      • CLEC 13B antibody
      • CLEC13B antibody
      • DEC 205 antibody
      • DEC-205 antibody
      • DEC205 antibody
      • gp200 antibody
      • gp200 MR6 antibody
      • gp200-MR6 antibody
      • LY 75 antibody
      • Ly-75 antibody
      • LY75 antibody
      • LY75_HUMAN antibody
      • Lymphocyte antigen 75 antibody
      • Renal Cell Carcinoma (gp200) antibody
      see all

    参考文献

    This product has been referenced in:
    • Reeh KA  et al. Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis. Development 141:2950-8 (2014). IHC-P ; Mouse . Read more (PubMed: 25053428) »
    • Jenkinson SR  et al. TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Proc Natl Acad Sci U S A 110:21107-12 (2013). Mouse . Read more (PubMed: 24324158) »

    See all 7 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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