製品の概要

  • 製品名Anti-LTK antibody
    LTK 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LTK
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to amino acids 57-73 of Human LTK.

  • ポジティブ・コントロール
    • Placenta lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab5507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 92 kDa (predicted molecular weight: 96 kDa).

ターゲット情報

  • 機能Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
  • 組織特異性Expressed in non-hematopoietic cell lines and T- and B-cell lines.
  • 関連疾患Note=Genetic variations in LTK that cause up-regulation of the PI3K pathway may possibly contribute to susceptibility to abnormal proliferation of self-reactive B cells and, therefore, to systemic lupus erythematosus (SLE). SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue, thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Leukocyte receptor tyrosine kinase antibody
    • Leukocyte tyrosine kinase antibody
    • Leukocyte tyrosine kinase receptor antibody
    • Ltk antibody
    • LTK_HUMAN antibody
    • Protein tyrosine kinase 1 antibody
    • TYK 1 antibody
    • TYK1 antibody
    see all

Anti-LTK antibody 画像



  • Predicted band size : 96 kDa

Anti-LTK antibody (ab5507) 使用論文

ab5507 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"