This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

製品の概要

製品の特性

アプリケーション

  • 追加情報This antibody gave a positive result in ELISA against the immunizing peptide (ab34463).
    Not yet tested in other applications.

  • ターゲット情報

    • 機能Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.
    • 配列類似性Belongs to the flavin monoamine oxidase family.
      Contains 1 CW-type zinc finger.
      Contains 1 SWIRM domain.
    • ドメインThe SWIRM domain may act as an anchor site for a histone tail.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 製品の状態There are 3 isoforms produced by alternative splicing.
    • 別名
      • amine oxidase (flavin containing) domain 1 antibody
      • amine oxidase, flavin containing 1 antibody
      • AOF1 antibody
      • bA204B7.3 antibody
      • C6orf193 antibody
      • dJ298J15.2 antibody
      • Flavin-containing amine oxidase domain-containing protein 1 antibody
      • FLJ33898 antibody
      • FLJ34109 antibody
      • FLJ43328 antibody
      • KDM1B antibody
      • KDM1B_HUMAN antibody
      • LSD2 antibody
      • lysine (K)-specific demethylase 1B antibody
      • Lysine-specific demethylase 2 antibody
      • Lysine-specific histone demethylase 1B antibody
      • Lysine-specific histone demethylase 2 antibody
      see all

    Anti-LSD2 / AOF1 antibody (ab34464) 使用論文

    ab34464 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab34464.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"