製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to LRRC26
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 288-319 of Human LRRC26 (NP_001013675.1).

  • ポジティブ・コントロール
    • A549 cell line lysate
  • 特記事項
    Store in small aliquots and prevent freeze-thaw cycles

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • 特記事項(精製)
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.

ターゲット情報

  • 機能
    Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.
  • 組織特異性
    Isoform 1 is expressed highly in normal prostate and salivary gland, very weakly in colon, pancreas, and intestine, and not at all in other tissues. Isoform 1 is expressed highly in many cancer cell lines and in breast cancer, pancreatic cancer and colon cancer. Isoform 2 is expressed in cancer cell lines.
  • 配列類似性
    Contains 5 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • ドメイン
    The transmembrane domain is necessary for interaction with KCNMA1.
  • 細胞内局在
    Membrane. Cytoplasm > cytoskeleton. Although predicted to be a single-pass type I membrane protein, this protein localizes to the cytoplasm when expressed at high levels.
  • Information by UniProt
  • 参照データベース
  • 製品の状態
    There are 2 isoforms produced by alternative splicing. Isoform 1 = L-CAPC. Isoform 2 = S-CAPC and does not contain the immunogen sequence.
  • 別名
    • bA350O14.10 antibody
    • CAPC antibody
    • cytokeratin-associated protein antibody
    • Cytokeratin-associated protein in cancer antibody
    • Leucine-rich repeat-containing protein 26 antibody
    • LRC26_HUMAN antibody
    • Lrrc26 antibody
    see all

画像

  • Anti-LRRC26 antibody (ab124181) at 1/100 dilution + A549 cell line lysate at 35 µg

    Predicted band size : 34 kDa

プロトコール

参考文献

ab124181 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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