製品の概要

  • 製品名
    Anti-LRP3 antibody
  • 製品の詳細
    Rabbit polyclonal to LRP3
  • アプリケーション
    適用あり: IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Monkey
  • 免疫原

    Synthetic peptide corresponding to Human LRP3 aa 676-693 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    EVGPSGPPLPSGLRDPEC

  • ポジティブ・コントロール
    • Human skin tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA 1/1000.

ターゲット情報

  • 機能
    Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
  • 組織特異性
    Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
  • 配列類似性
    Belongs to the LDLR family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
  • 細胞内局在
    Membrane. Membrane > coated pit.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 105 kDa low-density lipoprotein receptor-related protein antibody
    • CTD-2540B15.13 antibody
    • hLRp105 antibody
    • Low density lipoprotein receptor related protein 3 antibody
    • Low-density lipoprotein receptor-related protein 3 antibody
    • LRP-3 antibody
    • Lrp3 antibody
    • LRP3_HUMAN antibody
    see all

画像

  • Immunohistochemistry Image of Human Skin (formalin-fixed, paraffin-embedded) stained with LRP3 antibody (ab115197) at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

プロトコール

参考文献

ab115197 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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