製品の概要

  • 製品名Anti-LRIG1 antibody
    LRIG1 一次抗体 製品一覧
  • 製品の詳細
    Chicken polyclonal to LRIG1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to part of the cytoplasmic tail (C-terminal part).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS, pH 8
  • Concentration information loading...
  • 精製度IgY fraction
  • ポリ/モノポリクローナル
  • アイソタイプIgY
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab58853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1 µg/ml, performed on lysates from over-expressing cells. Predicted molecular weight: 120 kDa.

    LRIG1 protein migrates during denaturing polyacrylamide gel electrophoresis under reducing conditions as two species with apparent molecular weights of 143kDa and 134kDa, and as two fragments corresponding to an N-terminal 111kDa species and a C-terminal 32kDa species. Under non-reducing conditions, both apparent monomers and apparent higher molecular weight complexes were evident.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
    • 組織特異性Widely expressed.
    • 配列類似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 15 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • ドメインThe LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Leucine rich repeat protein antibody
      • Leucine rich repeat protein LRIG1 antibody
      • leucine rich repeats and immunoglobulin like domains 1 antibody
      • Leucine-rich repeats and immunoglobulin-like domains protein 1 antibody
      • leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1 antibody
      • LIG 1 antibody
      • LIG-1 antibody
      • LIG1 antibody
      • Lrig1 antibody
      • LRIG1_HUMAN antibody
      • Ortholog of mouse integral membrane glycoprotein LIG 1 antibody
      see all

    Anti-LRIG1 antibody (ab58853) 使用論文

    ab58853 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab58853.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"