製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to LRFN2
  • アプリケーション
    適用あり: ICC/IF, IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 14 aa from near the C-terminus of Human LRFN2 (Q9ULH4).

  • ポジティブ・コントロール
    • Rat brain tissue lysate, Mouse brain tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 85 kDa.

ターゲット情報

  • 機能
    Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery.
  • 配列類似性
    Belongs to the LRFN family.
    Contains 1 fibronectin type-III domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • ドメイン
    The PDZ-binding motif is required for cell surface expression, neurite outgrowth promotion (By similarity). This motif is also involved in DLG1-, DLG3- and DLG4-binding.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Membrane. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • fibronectin type III, immunoglobulin and leucine rich repeat domains 2 antibody
    • FIGLER2 antibody
    • KIAA1246 antibody
    • leucine rich repeat and fibronectin type III domain containing 2 antibody
    • Leucine-rich repeat and fibronectin type-III domain-containing protein 2 antibody
    • LRFN2 antibody
    • LRFN2_HUMAN antibody
    • RP11-535K1.2 antibody
    • SALM1 antibody
    • Synaptic adhesion-like molecule 1 antibody
    see all

画像

  • Immunofluorescence of LRFN2 in mouse brain tissue with ab106366 at 20 ug/mL.

  • Lane 1 : Anti-LRFN2 antibody (ab106366) at 1 µg/ml
    Lane 2 : Anti-LRFN2 antibody (ab106366) at 2 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate

    Lysates/proteins at 15 µg/ml per lane.


    Predicted band size : 85 kDa
  • ab106366, at 2.5 ug/ml, staining LRFN2 in Mouse brain tissue by immunohistochemistry.

参考文献

ab106366 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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