製品の概要

  • 製品名
    Anti-LOXL3 antibody
  • 製品の詳細
    Rabbit polyclonal to LOXL3
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: KRVNAAFYRL LAQRQQHSFG LHGVACVGTE AHLSLCSLEF YRANDTARCP, corresponding to amino acids 223-272 of Human LOXL3.

  • ポジティブ・コントロール
    • Human placenta tissue; RT 4 and U 251 MG cell lysates, Human tonsil lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/250.
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 組織特異性
    Expressed in many tissues, the highest levels among the tissues studied being seen in the placenta, heart, ovary, testis, small intestine and spleen.
  • 配列類似性
    Belongs to the lysyl oxidase family.
    Contains 4 SRCR domains.
  • 翻訳後修飾
    The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
  • 細胞内局在
    Secreted > extracellular space.
  • Information by UniProt
  • 参照データベース
  • 別名
    • LOXL antibody
    • Loxl3 antibody
    • LOXL3_HUMAN antibody
    • Lysyl oxidase homolog 3 antibody
    • Lysyl oxidase like 3 antibody
    • Lysyl oxidase-like protein 3 antibody
    see all

画像

  • ab122263, at 1/30, staining LOXL3 in paraffin embedded Human placenta tissue by Immunohistochemistry.
  • All lanes : Anti-LOXL3 antibody (ab122263) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique

参考文献

This product has been referenced in:
  • Mižíková I  et al. Collagen and elastin cross-linking is altered during aberrant late lung development associated with hyperoxia. Am J Physiol Lung Cell Mol Physiol 308:L1145-58 (2015). Read more (PubMed: 25840994) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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