製品の概要

  • 製品名Anti-LMAN1 antibody
    LMAN1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LMAN1
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    FDSFDNDGKKNNPAI

    , corresponding to amino acids 159-173 of Rat LMAN1

  • ポジティブ・コントロール
    • Rat brain lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab32583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent concentration.
WB 1/1000. Detects a band of approximately 57.5 kDa.

ターゲット情報

  • 機能Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
  • 組織特異性Ubiquitous.
  • 関連疾患Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal.
  • 配列類似性Contains 1 L-type lectin-like domain.
  • 翻訳後修飾The N-terminal may be partly blocked.
  • 細胞内局在Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Endoplasmic reticulum golgi intermediate compartment protein 53 antibody
    • ER-Golgi intermediate compartment 53 kDa protein antibody
    • ERGIC-53 antibody
    • ERGIC53 antibody
    • ERGIC53 like protein antibody
    • F5F8D antibody
    • FMFD1 antibody
    • Gp58 antibody
    • Intracellular mannose specific lectin antibody
    • Intracellular mannose-specific lectin MR60 antibody
    • Lectin mannose binding 1 antibody
    • Lectin mannose-binding 1 antibody
    • Lman1 antibody
    • LMAN1 like protein antibody
    • LMAN1_HUMAN antibody
    • MCFD1 antibody
    • MR60 antibody
    • Protein ERGIC-53 antibody
    see all

Anti-LMAN1 antibody 画像

  • ab32583 labelling LMAN1 in p19 cells by Immunocytochemistry/Immunofluorescence.

  • ab32583 labelling LMAN1 in HMVEC cells by Immunocytochemistry/Immunofluorescence.

  • ab32583 labelling LMAN1 in A549 cells by Immunocytochemistry/Immunofluorescence.

  • All lanes : Anti-LMAN1 antibody (ab32583) at 1/1000 dilution

    Lane 1 : Rat brain lysate
    Lane 2 : Rat brain lysate with Immunising peptide


    Observed band size : 57.5 kDa (why is the actual band size different from the predicted?)

Anti-LMAN1 antibody (ab32583) 使用論文

ab32583 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"