Anti-LLGL2 抗体 (ab73304)
Key features and details
- Rabbit polyclonal to LLGL2
- Suitable for: ELISA, IHC, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-LLGL2 antibody -
製品の詳細
Rabbit polyclonal to LLGL2 -
由来種
Rabbit -
特異性
Reacts specifically with human 113 kDa protein. -
アプリケーション
適用あり: ELISA, IHC, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide derived from N terminal domain of human LLGL2 protein
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab73304の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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IHC |
1/100 - 1/1000.
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WB |
1/1000 - 1/5000. Predicted molecular weight: 113 kDa.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
IHC
1/100 - 1/1000. |
WB
1/1000 - 1/5000. Predicted molecular weight: 113 kDa. |
ターゲット情報
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機能
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. -
配列類似性
Belongs to the WD repeat L(2)GL family.
Contains 14 WD repeats. -
翻訳後修飾
Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex. -
細胞内局在
Cytoplasm. Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells. - Information by UniProt
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参照データベース
- Entrez Gene: 3993 Human
- Entrez Gene: 217325 Mouse
- Entrez Gene: 360661 Rat
- SwissProt: Q6P1M3 Human
- SwissProt: Q3TJ91 Mouse
- Unigene: 514477 Human
- Unigene: 290450 Mouse
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別名
- HGL antibody
- Human giant larvae homolog antibody
- L2GL2 antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab73304 は 1 報の論文で使用されています。
- Xu Y et al. TGF-β3 induces lactate production in Sertoli cell through inhibiting the Notch pathway. Andrology 10:1644-1659 (2022). PubMed: 36057850