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ab15095 は 24 報の論文で使用されています。

  • Imasawa T  et al. High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy. FASEB J 31:294-307 (2017). WB ; Human . PubMed: 27825100
  • Yao YH  et al. Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non-small cell lung cancer cells. Chin J Cancer 35:50 (2016). PubMed: 27266881
  • Sun L  et al. 2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells. PLoS One 11:e0168793 (2016). PubMed: 28033353
  • Calles A  et al. Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma. Clin Cancer Res 21:2851-60 (2015). PubMed: 25737507
  • Yang SH  et al. Lovastatin overcomes gefitinib resistance through TNF-a signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget 6:23857-73 (2015). WB . PubMed: 26160843
  • Grossi V  et al. Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38. Autophagy 11:2102-2113 (2015). PubMed: 26391455
  • Houde VP  et al. Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity. Biochem J 458:41-56 (2014). PubMed: 24295069
  • Werle K  et al. Liver kinase B1 regulates the centrosome via PLK1. Cell Death Dis 5:e1157 (2014). PubMed: 24722282
  • Shen YA  et al. Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent. Nat Commun 5:4991 (2014). PubMed: 25255972
  • Mack HI & Munger K The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines. Virology 446:9-16 (2013). PubMed: 24074562
  • Nakada Y  et al. The LKB1 Tumor Suppressor as a Biomarker in Mouse and Human Tissues. PLoS One 8:e73449 (2013). IHC-P ; Human . PubMed: 24086281
  • Lützner N  et al. FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop. PLoS One 7:e42166 (2012). Human . PubMed: 22848740
  • Lin YY  et al. Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature 482:251-5 (2012). PubMed: 22318606
  • Lützner N  et al. Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors. PLoS One 7:e32590 (2012). WB ; Human . PubMed: 22412893
  • Foretz M  et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest 120:2355-69 (2010). WB ; Mouse . PubMed: 20577053
  • Eid AA  et al. AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. J Biol Chem 285:37503-12 (2010). WB ; Mouse . PubMed: 20861022
  • Zhong D  et al. 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition. Mol Cancer Ther 7:809-17 (2008). WB ; Human . PubMed: 18413794
  • Zhang S  et al. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Res 68:740-8 (2008). ICC/IF ; Human . PubMed: 18245474
  • Carretero J  et al. Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer. Oncogene 26:1616-25 (2007). PubMed: 16953221
  • Partanen JI  et al. Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization. Proc Natl Acad Sci U S A 104:14694-9 (2007). PubMed: 17766436
  • Xu ZX  et al. A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase. Cell Death Differ 14:1948-57 (2007). WB ; Human . PubMed: 17690712
  • Liang J  et al. The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol 9:218-24 (2007). WB ; Human . PubMed: 17237771
  • Conde E  et al. Specific pattern of LKB1 and phospho-acetyl-CoA carboxylase protein immunostaining in human normal tissues and lung carcinomas. Hum Pathol 38:1351-60 (2007). PubMed: 17521700
  • Zhong D  et al. LKB1 mutation in large cell carcinoma of the lung. Lung Cancer 53:285-94 (2006). PubMed: 16822578