製品の概要

  • 製品名Anti-Livin antibody
    Livin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Livin
  • 特異性Detects both the alpha and beta (short and long) isoforms of Livin.
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    CRAPVRSRVRTFLS

    , corresponding to amino acids 264 - 280 (short form) or 281 - 298 (long form) of Human Livin.

  • ポジティブ・コントロール
    • WB: Raji cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab5393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF
WB
  • 追加情報WB: Use at a concentration of 2 - 4 µg/ml. Detects bands of approximately 30 kDa (possibly short form) + 33 kDa (long form).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
    • 組織特異性Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.
    • 配列類似性Belongs to the IAP family.
      Contains 1 BIR repeat.
      Contains 1 RING-type zinc finger.
    • 細胞内局在Nucleus. Cytoplasm. Nuclear, and in a filamentous pattern throughout the cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Baculoviral IAP repeat containing 7 antibody
      • Baculoviral IAP repeat containing protein 7 antibody
      • Baculoviral IAP repeat-containing protein 7 antibody
      • BIRC 7 antibody
      • birc7 antibody
      • BIRC7_HUMAN antibody
      • KIAP antibody
      • Kidney inhibitor of apoptosis protein antibody
      • Livin antibody
      • Livin inhibitor of apotosis antibody
      • Melanoma inhibitor of apoptosis protein antibody
      • ML IAP antibody
      • ML-IAP antibody
      • MLIAP antibody
      • RING finger protein 50 antibody
      • RNF 50 antibody
      • RNF50 antibody
      see all

    Anti-Livin antibody 画像

    • Anti-Livin antibody (ab5393) at 4 µg/ml + Human Raji cell lysate

      Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    • Immunofluorescence of Livin in Human Small Intestine cells using ab5393 at 20 ug/ml.

    Anti-Livin antibody (ab5393) 使用論文

    ab5393 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab5393.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"