製品の概要

  • 製品名
    Lithium chloride
  • 製品の詳細
    GSK3β inhibitor
  • 生理活性の詳細
    Direct, non-competitive GSK3β inhibitor in vitro (Ki = 2 mM). Elicits various neuropharmacological effects.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Makoukji J  et al. Lithium enhances remyelination of peripheral nerves. Proc Natl Acad Sci U S A 109:3973-8 (2012). Read more (PubMed: 22355115) »
  • Pan JQ  et al. AKT kinase activity is required for lithium to modulate mood-related behaviors in mice. Neuropsychopharmacology 36:1397-411 (2011). Read more (PubMed: 21389981) »
  • Zhu Q  et al. Suppression of glycogen synthase kinase 3 activity reduces tumor growth of prostate cancer in vivo. Prostate 71:835-45 (2011). Read more (PubMed: 21456066) »
  • Klein PS & Melton DA A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 93:8455-9 (1996). Read more (PubMed: 8710892) »

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