製品の概要

  • 製品名Anti-LIPI antibody
    LIPI 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LIPI
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (YFVLSIIVPD KTMMDGSFSF KLLNQLGMIE EPRLYEKNKP FYKLQEVKIL) of Human LIPI (NP_945347).

  • ポジティブ・コントロール
    • NCI-H226 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
  • 組織特異性Expressed in testis. Expressed exclusively at the connecting piece of the sperm.
  • 関連疾患Defects in LIPI may be a cause of susceptibility to familial hypertriglyceridemia (FHTR)[MIM:145750]. Familial hypertriglyceridemia is a common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis.
  • 配列類似性Belongs to the AB hydrolase superfamily. Lipase family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Membrane. May associate with lipid draft and Membrane. Secreted. May associate with lipid draft.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cancer/testis antigen 17 antibody
    • CT17 antibody
    • Lipase member I antibody
    • LIPI antibody
    • LIPI_HUMAN antibody
    • LPD lipase antibody
    • LPDL antibody
    • Membrane-associated phosphatidic acid-selective phospholipase A1-beta antibody
    • membrane-associated phospholipase A1 beta 7B+ antibody
    • membrane-associated phospholipase A1 beta deltaE2-3 antibody
    • membrane-associated phospholipase A1 beta deltaE5 antibody
    • membrane-associated phospholipase A1 beta deltaE6.1 antibody
    • membrane-associated phospholipase A1 beta deltaE7.2 antibody
    • membrane-associated phospholipase A1 beta deltaE8-9 antibody
    • membrane-associated phospholipase A1 beta fl antibody
    • mPA-PLA1 beta antibody
    • PLA1C antibody
    • PRED5 antibody
    see all

Anti-LIPI antibody 画像

  • Anti-LIPI antibody (ab106123) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

    Predicted band size : 53 kDa

Anti-LIPI antibody (ab106123) 使用論文

ab106123 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"