製品の概要

  • 製品名Anti-LIM kinase 2 antibody
    LIM kinase 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LIM kinase 2
  • 特異性ab39659 detects endogenous levels of total LIM kinase 2 protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide (non-phosphopeptide derived) from Human LIM kinase 2 around the phosphorylation site of Threonine 505.

  • ポジティブ・コントロール
    • NIH/3T3 (Mouse embryonic fibroblast cell line) cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab39659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
ELISA 1/4000.

ターゲット情報

  • 機能Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.
  • 組織特異性Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.
  • 配列類似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 2 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Phosphorylated on serine and/or threonine residues by ROCK1.
  • 細胞内局在Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • LIM domain kinase 2 antibody
    • LIMK 2 antibody
    • LIMK-2 antibody
    • Limk2 antibody
    • LIMK2_HUMAN antibody
    see all

Anti-LIM kinase 2 antibody 画像

  • All lanes : Anti-LIM kinase 2 antibody (ab39659) at 1/500 dilution

    Lane 1 : NIH/3T3 with UV
    Lane 2 : A2780 without UV


    Predicted band size : 72 kDa
    Observed band size : 72 kDa

Anti-LIM kinase 2 antibody (ab39659) 使用論文

ab39659 has not yet been referenced specifically in any publications.

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