製品の概要

  • 製品名Anti-LILRB2 antibody
    LILRB2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to LILRB2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 22-599 of Human LILRB2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
    • 組織特異性Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.
    • 配列類似性Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
    • ドメインContains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
    • 翻訳後修飾Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD85 antigen-like family member D antibody
      • CD85d antibody
      • CD85d antigen antibody
      • ILT 4 antibody
      • ILT-4 antibody
      • ILT4 antibody
      • Immunoglobulin like transcript 4 antibody
      • Immunoglobulin-like transcript 4 antibody
      • Leukocyte immunoglobulin like receptor 2 antibody
      • Leukocyte immunoglobulin like receptor subfamily B member 2 antibody
      • Leukocyte immunoglobulin-like receptor 2 antibody
      • Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody
      • Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 antibody
      • LILRA6 antibody
      • LILRB2 antibody
      • LIR 2 antibody
      • LIR-2 antibody
      • LIR2 antibody
      • LIRb antibody
      • LIRB2_HUMAN antibody
      • MIR 10 antibody
      • MIR-10 antibody
      • MIR10 antibody
      • Monocyte/macrophage immunoglobulin like receptor 10 antibody
      • Monocyte/macrophage immunoglobulin-like receptor 10 antibody
      see all

    Anti-LILRB2 antibody 画像



    • Predicted band size : 65 kDa
      LILRB2 antibody (ab56696) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-LILRB2 antibody (ab56696) 使用論文

    This product has been referenced in:
    • Isnardi I  et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood 115:5026-36 (2010). Read more (PubMed: 20231422) »

    See 1 Publication for this product

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Mouse Cell (Mouse Stem Cells)
    Specification Mouse Stem Cells
    Fixative Paraformaldehyde
    Permeabilization Yes - Triton-x
    Blocking step Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    Abcam user community

    Verified customer

    投稿 May 02 2012

    We are sorry to here that you are unable to take advantage of our abreview program. Unfortunately we do not offer the types of programs that you have mentioned (free sample/deduction). If in the future you would like to use our abreview program please ...

    Read More

    Thank you very much for your interest in ab56696. To our knowledge, ab56696 has not been tested in IHC. Therefore, I can offer a discount off a future purchase if you buy ab56696 now, test it in IHC and submit feedback to us in the form of an Abreview....

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"