FITC Anti-ILT-4 抗体 [27D6] (ab95819)
Key features and details
- FITC Rat monoclonal [27D6] to ILT-4
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgM
製品の概要
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製品名
FITC Anti-ILT-4 antibody [27D6]
ILT-4 一次抗体 製品一覧 -
製品の詳細
FITC Rat monoclonal [27D6] to ILT-4 -
由来種
Rat -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ・コントロール
- Normal Human peripheral blood cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: BSA, Gelatin, PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
27D6 -
アイソタイプ
IgM -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95819の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 5µl for 106 cells.
ab35774 - Rat monoclonal IgM, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 5µl for 106 cells. ab35774 - Rat monoclonal IgM, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. -
組織特異性
Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells. -
配列類似性
Contains 4 Ig-like C2-type (immunoglobulin-like) domains. -
ドメイン
Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. -
翻訳後修飾
Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 10288 Human
- Omim: 604815 Human
- SwissProt: Q8N423 Human
- Unigene: 655652 Human
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別名
- CD85 antigen-like family member D antibody
- CD85d antibody
- CD85d antigen antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (0)
ab95819 は論文での使用が確認できていません。