Anti-LFA3 抗体 [HI58a] (CF405M) (ab117738)

製品の概要

  • 製品名Anti-LFA3 antibody [HI58a] (CF405M)
    LFA3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [HI58a] to LFA3 (CF405M)
  • 標識CF405M. Ex: 408nm, Em: 452nm
  • 特異性ab117738 is recommended for use in flow cytometry for identification of erythrocytes, platelets, monocytes, bone marrow cells, a lymphocyte subset and epithelial and endothelial cells.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Peripheral Blood Mononuclear Cell

  • ポジティブ・コントロール
    • Normal Human peripheral blood cells
  • 特記事項


    ab117738 recognizes the Human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria

    CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーpH: 7.20
    Preservative: 0.09% Sodium azide
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 一次抗体 備考ab117738 recognizes the Human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria
  • ポリ/モノモノクローナル
  • クローン名HI58a
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 5µl for 106 cells. ab126026-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
  • 配列類似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AG3 antibody
    • CD58 antibody
    • CD58 antigen (lymphocyte function associated antigen 3)1 antibody
    • CD58 antigen antibody
    • CD58 antigen, (lymphocyte function associated antigen 3) antibody
    • CD58 molecule antibody
    • FLJ23181 antibody
    • FLJ43722 antibody
    • LFA 3 antibody
    • LFA-3 antibody
    • LFA3 antibody
    • LFA3_HUMAN antibody
    • Lymphocyte Function Associated Antigen Type 3 antibody
    • Lymphocyte function-associated antigen 3 antibody
    • Surface glycoprotein LFA 3 antibody
    • Surface glycoprotein LFA-3 antibody
    see all

Anti-LFA3 antibody [HI58a] (CF405M) 画像

  • Staining of normal Human peripheral blood cells with ab117738. Cells in the Lymphocytes gate were used for analysis (red histogram).

Anti-LFA3 antibody [HI58a] (CF405M) (ab117738) 使用論文

ab117738 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"