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Peripheral Blood Mononuclear Cell
ab117738 recognizes the Human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria
CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.
Our Abpromise guarantee covers the use of ab117738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 5µl for 106 cells. ab126026-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.|
ab117738 has not yet been referenced specifically in any publications.