製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to LEPREL1
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 177-288 of Human LEPREL1.

  • ポジティブ・コントロール
    • Human placenta tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
  • 組織特異性
    Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.
  • 配列類似性
    Belongs to the leprecan family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 4 TPR repeats.
  • 細胞内局在
    Endoplasmic reticulum. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 4832416N06 antibody
    • AW553532 antibody
    • Leprecan like 1 antibody
    • Leprecan-like protein 1 antibody
    • Leprel1 antibody
    • MCVD antibody
    • MLAT4 antibody
    • Myxoid liposarcoma-associated protein 4 antibody
    • P3H2 antibody
    • P3H2_HUMAN antibody
    • Prolyl 3 hydroxylase 3 antibody
    • Prolyl 3-hydroxylase 2 antibody
    see all

画像

  • ab121393, at 1/50 dilution, staining LEPREL1 in paraffin-embedded Human placenta tissue by Immunohistochemistry, showing strong cytoplasmic positivity in trophoblastic cells and decidual cells.

プロトコール

参考文献

ab121393 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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