製品の概要

  • 製品名Anti-LEFTY2 antibody
    LEFTY2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to LEFTY2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 77-180 of human LEFTY2 protein (NP_003231) with a proprietary tag.

  • ポジティブ・コントロール
    • Human skeletal muscle tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88088 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
  • 組織特異性Mesenchymal cells of the endometrial stroma.
  • 関連疾患Defects in LEFTY2 are the cause of left-right axis malformations (LRAM) [MIM:601877]. The defect includes left pulmonary isomerism, with cardiac anomalies characterized by complete atrioventricular canal defect and hypoplastic left ventricle, and interrupted inferior vena cava.
  • 配列類似性Belongs to the TGF-beta family.
  • 発生段階Transiently expressed before and during menstrual bleeding.
  • 翻訳後修飾The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EBAF antibody
    • Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily) antibody
    • Endometrial bleeding associated factor antibody
    • Endometrial bleeding-associated factor antibody
    • Left right determination factor 2 antibody
    • Left right determination factor A antibody
    • Left-right determination factor 2 antibody
    • Left-right determination factor A antibody
    • LEFTA antibody
    • LEFTY 2 antibody
    • LEFTY2 antibody
    • LEFTYA antibody
    • LFTY2 transforming growth factor, beta -4 antibody
    • LFTY2, mouse, homolog of antibody
    • LFTY2_HUMAN antibody
    • MGC46222 antibody
    • Protein lefty 2 antibody
    • Protein lefty A antibody
    • Protein lefty-2 antibody
    • Protein lefty-A antibody
    • Protein lefty2 antibody
    • PSEC0024 antibody
    • TGF beta 4 antibody
    • TGF-beta-4 antibody
    • TGFB4 antibody
    • Transforming growth factor beta 4 antibody
    • Transforming growth factor beta-4 antibody
    see all

Anti-LEFTY2 antibody 画像

  • Anti-LEFTY2 antibody (ab88088) at 5 µg/ml + human skeletal muscle lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 41 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

Anti-LEFTY2 antibody (ab88088) 使用論文

ab88088 has not yet been referenced specifically in any publications.

Product Wall

Vielen Dank für Ihre Anfrage.

Da die beiden Proteine sehr homolog sind und das Immunogen im Speziellen eine Homologie von 98% aufweist, gehen wir davon aus, dass LEFTY1 von ab88088 auch erkannt wird.

Dies wurde jedoch nicht exp...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"