Anti-LECT1 抗体 - Carboxyterminal end (ab71450)

製品の概要

  • 製品名Anti-LECT1 antibody - Carboxyterminal end
    LECT1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LECT1 - Carboxyterminal end
  • アプリケーション適用あり: IHC-P, ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rabbit
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human LECT1.

  • ポジティブ・コントロール
    • NCI-H460 membrane lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab71450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/10 - 1/50.
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 37 kDa.

ターゲット情報

  • 機能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • 組織特異性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • 配列類似性Belongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • 発生段階Expressed at 9 weeks in developing cartilagenous bone rudiments.
  • 翻訳後修飾After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • 細胞内局在Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BRICD3 antibody
    • BRICHOS domain containing 3 antibody
    • CH-SP antibody
    • CHM I antibody
    • ChM-I antibody
    • CHM1 antibody
    • chondromodulin antibody
    • Chondromodulin I antibody
    • Chondromodulin-1 antibody
    • Chondromodulin-I antibody
    • Chondrosurfactant protein antibody
    • LECT 1 antibody
    • Lect1 antibody
    • LECT1_HUMAN antibody
    • Leukocyte cell derived chemotaxin 1 antibody
    • Multiple myeloma tumor suppressor 1 antibody
    • MYETS1 antibody
    see all

Anti-LECT1 antibody - Carboxyterminal end 画像

  • Anti-LECT1 antibody - Carboxyterminal end (ab71450) at 1/60 dilution + NCI-H460 cell line lysates at 12.5 µg

    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-LECT1 antibody - Carboxyterminal end (ab71450) 使用論文

ab71450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"