製品の概要

  • 製品名Anti-LECT1 antibody
    LECT1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to LECT1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein (Human) LECT1 (NP_008946.1).

  • ポジティブ・コントロール
    • LECT1 transfected 293T lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 39 kDa).

ターゲット情報

  • 機能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • 組織特異性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • 配列類似性Belongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • 発生段階Expressed at 9 weeks in developing cartilagenous bone rudiments.
  • 翻訳後修飾After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • 細胞内局在Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BRICD3 antibody
    • BRICHOS domain containing 3 antibody
    • CH-SP antibody
    • CHM I antibody
    • ChM-I antibody
    • CHM1 antibody
    • chondromodulin antibody
    • Chondromodulin I antibody
    • Chondromodulin-1 antibody
    • Chondromodulin-I antibody
    • Chondrosurfactant protein antibody
    • LECT 1 antibody
    • Lect1 antibody
    • LECT1_HUMAN antibody
    • Leukocyte cell derived chemotaxin 1 antibody
    • Multiple myeloma tumor suppressor 1 antibody
    • MYETS1 antibody
    see all

Anti-LECT1 antibody 画像

  • All lanes : Anti-LECT1 antibody (ab68542) at 1/500 dilution

    Lane 1 : LECT1 293T transfected cell lysate
    Lane 2 : non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/5000 dilution

    Predicted band size : 39 kDa
    Observed band size : 43 kDa (why is the actual band size different from the predicted?)

Anti-LECT1 antibody (ab68542) 使用論文

ab68542 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab68542.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"