製品の概要

  • 製品名Anti-LDB1 antibody
    LDB1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to LDB1
  • アプリケーション適用あり: IHC-Fr, WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Pig, Zebrafish
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 50 and 345 of Human LDB1 (NP_003884)

  • ポジティブ・コントロール
    • 293T, A431, H1299, HeLa, Molt-4 and Raji cells. U87 xenograft.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.
IHC-P 1/100 - 1/250.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
  • 組織特異性Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 配列類似性Belongs to the LDB family.
  • ドメインThe dimerization domain is located in the N-terminus.
  • 翻訳後修飾Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carboxyl Terminal LIM Domain Binding 2 antibody
    • Carboxyl-terminal LIM domain-binding protein 2 antibody
    • CLIM 2 antibody
    • CLIM-2 antibody
    • hLdb1 antibody
    • LDB-1 antibody
    • ldb1 antibody
    • LDB1_HUMAN antibody
    • LIM Domain Binding 1 antibody
    • LIM domain binding factor CLIM2 antibody
    • LIM domain-binding factor CLIM2 antibody
    • LIM domain-binding protein 1 antibody
    • NLI antibody
    • Nuclear LIM Domain Interactor antibody
    • Nuclear LIM interactor antibody
    • xldb1 antibody
    see all

Anti-LDB1 antibody 画像

  • Anti-LDB1 antibody (ab96799) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 47 kDa
  • Immunofluorescence analysis of paraformaldheyde-fixed HeLa cells using ab96799 at a dilution of 1/200.
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft using ab96799 at a dilution of 1/100.

Anti-LDB1 antibody (ab96799) 使用論文

ab96799 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Mouse Brain)
Specification Mouse Brain
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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投稿 Dec 30 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"