特異性Recognizes human and rat LC3A/B-I and LC3A/B-II by immunoblotting and immunoprecipitation (~18 kDa and ~16 kDa, respectively). Recognizes mouse LC3A/B-I (~18 kDa). The detection of mouse LC3A/B-II may require specific cell treatment and/or long exposure.
Gao H et al. Rho-Kinase inhibitor fasudil suppresses high glucose-induced H9c2 cell apoptosis through activation of autophagy. Cardiovasc Ther34:352-9 (2016).
Read more (PubMed: 27333569) »
Marino FE et al. Activin-ßC modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways. J Cachexia Sarcopenia Muscle6:365-80 (2015).
Read more (PubMed: 26673867) »