製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to LBP
  • アプリケーション
    適用あり: ELISA, Flow Cyt, IP, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Affinity purified recombinant LBP (Human)

  • 特記事項


    ab25094 shows small inhibition of LPS binding to human CD14.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/100 - 1/1000.

Binding titer for human LBP: 1/3000.

Flow Cyt Use at an assay dependent concentration. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 53 kDa.

ターゲット情報

  • 機能
    Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
  • 配列類似性
    Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BPI fold containing family D, member 2 antibody
    • Bpifd2 antibody
    • LBP antibody
    • LBP_HUMAN antibody
    • LBP1 antibody
    • Lipopolysaccharide binding protein antibody
    • Lipopolysaccharide-binding protein antibody
    • LPS binding protein antibody
    • Ly88 antibody
    • MGC22233 antibody
    • OTTHUMP00000030965 antibody
    • RP23-407H16.4 antibody
    see all

参考文献

This product has been referenced in:
  • Zhu Y  et al. Beef, Chicken, and Soy Proteins in Diets Induce Different Gut Microbiota and Metabolites in Rats. Front Microbiol 8:1395 (2017). Read more (PubMed: 28798733) »
  • Haziak K  et al. Effects of central injection of anti-LPS antibody and blockade of TLR4 on GnRH/LH secretion during immunological stress in anestrous ewes. Mediators Inflamm 2014:867170 (2014). Sheep . Read more (PubMed: 24719525) »

See all 2 Publications for this product

レビューと Q&A

Thank you for contacting us. ab25094 and ab96748 were both raised against recombinant human LBP (full length and region 166-437 respectively). Unfortunately, comparing the human sequence to that of rat yielded only 68% homology. We would theref...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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