製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to LAP1
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH corresponding to the N-terminal residues of Human LAP1.

  • ポジティブ・コントロール
    • Human Brain (Cortex) tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 172 kDa.
ELISA Use a concentration of 1 µg/ml.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.
  • 組織特異性
    Brain-specific. Isoform 3 is ubiquitously expressed.
  • 配列類似性
    Belongs to the LAP (LRR and PDZ) protein family.
    Contains 17 LRR (leucine-rich) repeats.
    Contains 1 PDZ (DHR) domain.
  • 細胞内局在
    Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Densin 180 antibody
    • Densin antibody
    • Densin-180 antibody
    • densin180 antibody
    • DKFZp686I1147 antibody
    • KIAA1365 antibody
    • Lamin associated polypeptide 1 antibody
    • LAP 1 antibody
    • Leucine rich repeat containing 7 antibody
    • Leucine rich repeat containing protein 7 antibody
    • Leucine-rich repeat-containing protein 7 antibody
    • Lrrc 7 antibody
    • LRRC7 antibody
    • LRRC7_HUMAN antibody
    • MGC144918 antibody
    • OTTHUMP00000065336 antibody
    • OTTHUMP00000065337 antibody
    • OTTHUMP00000065338 antibody
    • Protein Lap 1 antibody
    • Protein lap1 antibody
    see all

画像

  • Immunohistochemistry Image of Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab115168 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

参考文献

ab115168 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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