Anti-LAMP2 抗体 [H4B4] (ab112019)


  • 製品名Anti-LAMP2 antibody [H4B4]
    LAMP2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [H4B4] to LAMP2
  • アプリケーション適用あり: WB, IHC-P, Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human LAMP2

  • ポジティブ・コントロール
    • Human Breast, Human Liver and Human Skin tissue; PBMCs and Jurkat cells lysates; Jurkat cells



Our Abpromise guarantee covers the use of ab112019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa.
IHC-P Use a concentration of 20 µg/ml.
Flow Cyt Use 0.5µg for 105-8 cells. in a final volume of 100 µl.

ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 機能Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
  • 組織特異性Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
  • 関連疾患Defects in LAMP2 are the cause of Danon disease (DAND) [MIM:300257]; also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes.
  • 配列類似性Belongs to the LAMP family.
  • 翻訳後修飾O- and N-glycosylated; some of the 16 N-linked glycans are polylactosaminoglycans.
  • 細胞内局在Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態Alternative splicing produces 3 isoforms.
  • 別名
    • CD107 antigen-like family member B antibody
    • CD107b antibody
    • LAMP 2 antibody
    • LAMP 2C antibody
    • LAMP-2 antibody
    • LAMP2 antibody
    • LAMP2_HUMAN antibody
    • LAMPB antibody
    • LGP110 antibody
    • Lysosomal associated membrane protein 2 antibody
    • Lysosome associated membrane protein 2 antibody
    • Lysosome-associated membrane glycoprotein 2 antibody
    • Lysosome-associated membrane protein 2 antibody
    • MAC3 antibody
    see all

Anti-LAMP2 antibody [H4B4] 画像

  • Immunohistochemical analysis of LAMP2 expression in formalin-fixed, paraffin-embedded Human breast tissue using ab112019 at 20 µg/ml.
  • Immunohistochemical analysis of LAMP2 expression in formalin-fixed, paraffin-embedded Human liver tissue using ab112019 at 20 µg/ml.
  • Immunohistochemical analysis of LAMP2 expression in formalin-fixed, paraffin-embedded Human skin tissue using ab112019 at 20 µg/ml.
  • All lanes : Anti-LAMP2 antibody [H4B4] (ab112019) at 1 µg/ml

    Lane 1 : PBMCs cell lysate
    Lane 2 : Jurkat cell lysate

    Lysates/proteins at 10 µg per lane.

    Predicted band size : 45 kDa

Anti-LAMP2 antibody [H4B4] (ab112019) 使用論文

ab112019 has not yet been referenced specifically in any publications.

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