Anti-Laminin 2 alpha 抗体 [2D4] (ab117608)

製品の概要

  • 製品名Anti-Laminin 2 alpha antibody [2D4]
    Laminin 2 alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2D4] to Laminin 2 alpha
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Human Laminin Alpha 2 (NP_000417.2).

  • ポジティブ・コントロール
    • Human Placenta (Trophoblast) tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab117608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 344 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
  • 組織特異性Placenta, striated muscle, peripheral nerve, cardiac muscle, pancreas, lung, spleen, kidney, adrenal gland, skin, testis, meninges, choroid plexus, and some other regions of the brain; not in liver, thymus and bone.
  • 関連疾患Defects in LAMA2 are the cause of merosin-deficient congenital muscular dystrophy type 1A (MDC1A) [MIM:607855]. MDC1A is characterized by difficulty walking, hypotonia, proximal weakness, hyporeflexia, and white matter hypodensity on MRI.
  • 配列類似性Contains 17 laminin EGF-like domains.
    Contains 5 laminin G-like domains.
    Contains 2 laminin IV type A domains.
    Contains 1 laminin N-terminal domain.
  • ドメインThe alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
    Domains VI, IV and G are globular.
  • 細胞内局在Secreted > extracellular space > extracellular matrix > basement membrane. Major component.
  • Information by UniProt
  • 参照データベース
  • 別名
    • LAMA 2 antibody
    • LAMA2 antibody
    • LAMA2_HUMAN antibody
    • Laminin alpha 2 (merosin congenital muscular dystrophy) antibody
    • Laminin alpha 2 antibody
    • Laminin alpha 2 chain antibody
    • Laminin alpha 2 subunit antibody
    • Laminin M antibody
    • Laminin M chain antibody
    • Laminin subunit alpha-2 antibody
    • Laminin-12 subunit alpha antibody
    • Laminin-2 subunit alpha antibody
    • Laminin-4 subunit alpha antibody
    • LAMM antibody
    • Merosin heavy chain antibody
    see all

Anti-Laminin 2 alpha antibody [2D4] 画像

  • ab117608, at 5 µg/ml, staining Laminin 2 alpha in Formalin-fixed, Paraffin-embedded Human Placenta (Trophoblast) tissue by Immunohistochemistry.

Anti-Laminin 2 alpha antibody [2D4] (ab117608) 使用論文

ab117608 has not yet been referenced specifically in any publications.

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