Anti-Lambda Light chain 抗体 [HP6054], prediluted (ab17112)

製品の概要

  • 製品名Anti-Lambda Light chain antibody [HP6054], prediluted
    Lambda Light chain 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [HP6054] to Lambda Light chain, prediluted
  • アプリケーション適用あり: IHC-Fr, IHC-Pmore details
  • 種交差性
    交差種: Human
    非交差種: Rat
  • 免疫原

    Purified human IgG myeloma proteins covalently linked to polyaminostyrene micro beads.

  • ポジティブ・コントロール
    • Tonsil
  • 特記事項


    This antibody stains B cell follicles in human lymphoid tissues. The mantle zone shows a mosaic pattern of labeling while the germinal centers show a coarse meshwork pattern of staining. Lambda light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non-Hodgkin's lymphomas.

製品の特性

  • 製品の状態Prediluted
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: Inert stabilizer
  • Concentration information loading...
  • 精製度Protein A purified
  • 一次抗体 備考This antibody stains B cell follicles in human lymphoid tissues. The mantle zone shows a mosaic pattern of labeling while the germinal centers show a coarse meshwork pattern of staining. Lambda light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non-Hodgkin's lymphomas.
  • ポリ/モノモノクローナル
  • クローン名HP6054
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab17112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr 1/1.

Acetone fixed. Prediluted and ready to use. An incubation period of 30 minutes at room temperature is recommended.

IHC-P 1/1. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Prediluted and ready to use. An incubation period of 30 minutes at room temperature is recommended. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

ターゲット情報

  • 関連性All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
  • 細胞内局在Cytoplasmic
  • 参照データベース
  • 別名
    • Bence Jones protein antibody
    • BJP antibody
    • Constant region of lambda light chains antibody
    • Ig lambda chain C regions antibody
    • ig lambda-6 chain C region antibody
    • IGLC 1 antibody
    • IGLC 2 antibody
    • IGLC 3 antibody
    • IGLC antibody
    • IGLC1 antibody
    • IGLC2 antibody
    • IGLC3 antibody
    • IGLC6 antibody
    • IGLV antibody
    • Immunoglobulin lambda constant 1 antibody
    • Immunoglobulin lambda constant regin 1 antibody
    • immunoglobulin lambda gene cluster antibody
    • Immunoglobulin lambda locus antibody
    • Immunoglobulin lambda variable cluster antibody
    • Immunoglobulin: lambda light chain antibody
    • Mcg marker antibody
    • Paraprotein antibody
    see all

Anti-Lambda Light chain antibody [HP6054], prediluted 画像

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human tonsil tissue sections, labelling Lambda Light Chain with ab17112.

Anti-Lambda Light chain antibody [HP6054], prediluted (ab17112) 使用論文

ab17112 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"