Anti-Lambda Light chain 抗体 [GA170] (Phycoerythrin) (ab1198)

製品の概要

  • 製品名
    Anti-Lambda Light chain antibody [GA170] (Phycoerythrin)
    Lambda Light chain 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [GA170] to Lambda Light chain (Phycoerythrin)
  • 標識
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性
    This antibody reacts with lambda light chains of human immunoglobulins.
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    PBS with 0.5% BSA and 0.1% sodium azide
  • Concentration information loading...
  • ポリ/モノ
    モノクローナル
  • クローン名
    GA170
  • ミエローマ
    unknown
  • アイソタイプ
    IgG2a
  • 軽鎖の種類
    unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab1198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Measurement of lambda light chain in human lysed whole peripheral blood or mononuclear cells separated by density gradient.
    Studies of clonality of B cell lymphomas in tissue.
    Studies of clonality of B cell leukemias in peripheral blood.

    Lambda (PE) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers.

    10µl ofLambda (PE) is sufficient for labelling of 1x106 cells.
  • ターゲット情報

    • 関連性
      All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
    • 細胞内局在
      Cytoplasmic
    • 参照データベース
    • 別名
      • Bence Jones protein antibody
      • BJP antibody
      • Constant region of lambda light chains antibody
      • Ig lambda chain C regions antibody
      • ig lambda-6 chain C region antibody
      • IGLC 1 antibody
      • IGLC 2 antibody
      • IGLC 3 antibody
      • IGLC antibody
      • IGLC1 antibody
      • IGLC2 antibody
      • IGLC3 antibody
      • IGLC6 antibody
      • IGLV antibody
      • Immunoglobulin lambda constant 1 antibody
      • Immunoglobulin lambda constant regin 1 antibody
      • immunoglobulin lambda gene cluster antibody
      • Immunoglobulin lambda locus antibody
      • Immunoglobulin lambda variable cluster antibody
      • Immunoglobulin: lambda light chain antibody
      • Mcg marker antibody
      • Paraprotein antibody
      see all

    プロトコール

    参考文献

    ab1198 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab1198.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録