製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to L2HGDH
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human L2HGDH aa 132-159 conjugated to keyhole limpet haemocyanin.
    Database link: Q9H9P8

  • ポジティブ・コントロール
    • MDA-MB435 cell line and Mouse kidney tissue lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 組織特異性
    Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
  • 関連疾患
    Defects in L2HGDH are the cause of L-2-hydroxyglutaric aciduria (L2HGA) [MIM:236792]. L2HGA is a rare autosomal recessive disorder clinically characterized by mild psychomotor delay in the first years of life, followed by progressive cerebellar ataxia, dysarthria and moderate to severe mental retardation. Diagnosis is based on the presence of an excess of L-2-hydroxyglutaric acid in urine, blood and cerebrospinal fluid.
  • 配列類似性
    Belongs to the L2HGDH family.
  • 細胞内局在
    Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2 hydroxyglutarate dehydrogenase antibody
    • Alpha hydroxyglutarate oxidoreductase antibody
    • Alpha ketoglutarate reductase antibody
    • C14orf160 antibody
    • Duranin antibody
    • FLJ12618 antibody
    • L alpha hydroxyglutarate dehydrogenase antibody
    • L-2-hydroxyglutarate dehydrogenase antibody
    • L-2-hydroxyglutarate dehydrogenase, mitochondrial antibody
    • L2HDH_HUMAN antibody
    • l2hgdh antibody
    • mitochondrial antibody
    see all

画像

  • All lanes : Anti-L2HGDH antibody (ab108012) at 1/1000 dilution

    Lane 1 : Mouse kidney tissue lysates
    Lane 2 : MDA-MB435 cell line

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 50 kDa

プロトコール

参考文献

ab108012 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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