製品の概要

  • 製品名Anti-L2HGDH antibody
  • 製品の詳細
    Rabbit polyclonal to L2HGDH
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 139-167 of Human L2HGDH (NP_079160.1).

  • ポジティブ・コントロール
    • MDA-MB435 cell line and Mouse kidney tissue lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab108012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 組織特異性Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
  • 関連疾患Defects in L2HGDH are the cause of L-2-hydroxyglutaric aciduria (L2HGA) [MIM:236792]. L2HGA is a rare autosomal recessive disorder clinically characterized by mild psychomotor delay in the first years of life, followed by progressive cerebellar ataxia, dysarthria and moderate to severe mental retardation. Diagnosis is based on the presence of an excess of L-2-hydroxyglutaric acid in urine, blood and cerebrospinal fluid.
  • 配列類似性Belongs to the L2HGDH family.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2 hydroxyglutarate dehydrogenase antibody
    • Alpha hydroxyglutarate oxidoreductase antibody
    • Alpha ketoglutarate reductase antibody
    • C14orf160 antibody
    • Duranin antibody
    • FLJ12618 antibody
    • L alpha hydroxyglutarate dehydrogenase antibody
    • L-2-hydroxyglutarate dehydrogenase antibody
    • L-2-hydroxyglutarate dehydrogenase, mitochondrial antibody
    • L2HDH_HUMAN antibody
    • l2hgdh antibody
    • mitochondrial antibody
    see all

Anti-L2HGDH antibody 画像

  • Anti-L2HGDH antibody (ab108012) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg/ml

    Predicted band size : 50 kDa
  • Anti-L2HGDH antibody (ab108012) at 1/100 dilution + Mouse kidney tissue lysates at 35 µg

    Predicted band size : 50 kDa

Anti-L2HGDH antibody (ab108012) 使用論文

ab108012 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab108012.
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