製品の概要

  • 製品名
    L-694,247
  • 製品の詳細
    Highly potent 5-HT1D/5-HT1B receptor agonist
  • 生理活性の詳細
    Highly potent, selective 5-HT1D/5-HT1B receptor agonist (pIC50 values are 10.03 and 9.08 at 5-HT1D and 5-HT1B receptors, respectively). Induces partial blockade of water intake.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Bhalla P  et al. Molecular cloning, pharmacological properties and tissue distribution of the porcine 5-HT(1B) receptor. Br J Pharmacol 133:891-901 (2001). Read more (PubMed: 11454663) »
  • De Castro-e-Silva E  et al. Effect of third ventricle administration of L-694,247, a selective 5-HT1D receptor agonist, on water intake in rats. Pharmacol Biochem Behav 57:749-54 (1997). Read more (PubMed: 9259002) »
  • Beer MS  et al. L-694,247: a potent 5-HT1D receptor agonist. Br J Pharmacol 110:1196-200 (1993). Read more (PubMed: 8298808) »

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