製品の概要

  • 製品名Anti-Kv4.3 antibody
    Kv4.3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Kv4.3
  • アプリケーション適用あり: IHC-P, IHC-Fr, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N terminal domain of human Kv4.3.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB 1/200 - 1/2000. Predicted molecular weight: 73 kDa.

ターゲット情報

  • 機能Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • 組織特異性Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.
  • 配列類似性Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
  • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 細胞内局在Membrane. Cell membrane > sarcolemma.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KCND 3 antibody
    • KCND 3L antibody
    • KCND 3S antibody
    • Kcnd3 antibody
    • KCND3_HUMAN antibody
    • KCND3L antibody
    • KCND3S antibody
    • KSHIVB antibody
    • Kv 4.3 antibody
    • MGC14203 antibody
    • MGC142037 antibody
    • OTTHUMP00000063948 antibody
    • Potassium ioinic channel Kv4.3 antibody
    • Potassium voltage gated channel Shal related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily D member 3 antibody
    • Potassium voltage-gated channel subfamily D member 3 antibody
    • Sha1 related potassium channel Kv4.3 antibody
    • Voltage gated K+ channel antibody
    • Voltage gated potassium channel Kv4.3 antibody
    • Voltage gated potassium channel subunit Kv4.3 antibody
    • Voltage-gated potassium channel subunit Kv4.3 antibody
    see all

Anti-Kv4.3 antibody (ab65794) 使用論文

This product has been referenced in:
  • Matkovich SJ  et al. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res 106:166-75 (2010). WB ; Human . Read more (PubMed: 19893015) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"