製品の概要

  • 製品名Anti-Kv4.3 antibody
    Kv4.3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Kv4.3
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Pig
  • 免疫原

    Synthetic peptide: AKTGSSNAYL HSKRNGLLNE ALELTGTPEE EHMGKTTSLI ESQHHHLLHC, corresponding to intracellular amino acids 433-482 of Human Kv4.3

  • ポジティブ・コントロール
    • HepG2 lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49348 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:12500.

WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 61, 42 kDa (predicted molecular weight: 70 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • 組織特異性Highly expressed in heart and brain, in particular in cortex, cerebellum, amygdala and caudate nucleus. Detected at lower levels in liver, skeletal muscle, kidney and pancreas. Isoform 1 predominates in most tissues. Isoform 1 and isoform 2 are detected at similar levels in brain, skeletal muscle and pancreas.
  • 配列類似性Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.3/KCND3 sub-subfamily.
  • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 細胞内局在Membrane. Cell membrane > sarcolemma.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KCND 3 antibody
    • KCND 3L antibody
    • KCND 3S antibody
    • Kcnd3 antibody
    • KCND3_HUMAN antibody
    • KCND3L antibody
    • KCND3S antibody
    • KSHIVB antibody
    • Kv 4.3 antibody
    • MGC14203 antibody
    • MGC142037 antibody
    • OTTHUMP00000063948 antibody
    • Potassium ioinic channel Kv4.3 antibody
    • Potassium voltage gated channel Shal related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily D member 3 antibody
    • Potassium voltage-gated channel subfamily D member 3 antibody
    • Sha1 related potassium channel Kv4.3 antibody
    • Voltage gated K+ channel antibody
    • Voltage gated potassium channel Kv4.3 antibody
    • Voltage gated potassium channel subunit Kv4.3 antibody
    • Voltage-gated potassium channel subunit Kv4.3 antibody
    see all

Anti-Kv4.3 antibody 画像

  • Anti-Kv4.3 antibody (ab49348) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG 1/50,000 -1/100,000

    Predicted band size : 70 kDa
    Observed band size : 60,61 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 42 kDa (possible non-specific binding).

Anti-Kv4.3 antibody (ab49348) 使用論文

ab49348 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam. I am sorry to hear that ab65794 has not been working for you. I will be glad to help you find an alternative antibody. To help determine the antibody that will best suit your needs, could you tell me what ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"