Anti-Kv1.2 抗体 - Carboxyterminal end (ab55987)

製品の概要

  • 製品名Anti-Kv1.2 antibody - Carboxyterminal end
    Kv1.2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Kv1.2 - Carboxyterminal end
  • アプリケーション適用あり: WB, ELISA, ICC/IFmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to C-terminal residues of mouse KCNA2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab55987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 1 - 5 µg/ml.

ターゲット情報

  • 関連性Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 細胞内局在Membrane; Multi-pass membrane protein
  • 参照データベース
  • 別名
    • Akr6a4 antibody
    • BK2 antibody
    • HBK5 antibody
    • HK4 antibody
    • HUKIV antibody
    • Kca1 2 antibody
    • kcna2 antibody
    • KV1.2 antibody
    • MGC50217 antibody
    • Mk 2 antibody
    • MK2 antibody
    • NGK1 antibody
    • Potassium voltage gated channel shaker related subfamily member 2 antibody
    • Potassium voltage-gated channel subfamily A member 2 antibody
    • RBK2 antibody
    • Voltage gated potassium channel subunit Kv1.2 antibody
    see all

Anti-Kv1.2 antibody - Carboxyterminal end 画像

  • ICC/IF image of ab55987 stained SHSY5Y cells. The cells were 4% formaldehyde fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab55987, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Kv1.2 antibody - Carboxyterminal end (ab55987) 使用論文

ab55987 has not yet been referenced specifically in any publications.

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