製品の概要

  • 製品名Anti-Kv beta 1 antibody [S40-17]
    Kv beta 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [S40-17] to Kv beta 1
  • アプリケーション適用あり: ICC/IF, IHC-P, IHC-Fr, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1 - 401 of Rat Kv beta 1 (P63144).

  • ポジティブ・コントロール
    • Rat brain lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20ºC.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名S40-17
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
IHC-P Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
IHC-Fr Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 - 45 kDa.

ターゲット情報

  • 機能Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.
  • 組織特異性In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
  • 配列類似性Belongs to the shaker potassium channel beta subunit family.
  • ドメインAlteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hKvb3 antibody
    • hKvBeta3 antibody
    • K(+) channel subunit beta-1 antibody
    • KCAB1_HUMAN antibody
    • KCNA1B antibody
    • KCNAB1 antibody
    • Kv-beta-1 antibody
    • Kvb1.3 antibody
    • Voltage-gated potassium channel beta-1 subunit antibody
    • Voltage-gated potassium channel subunit beta-1 antibody
    see all

Anti-Kv beta 1 antibody [S40-17] 画像

  • Image from David M et al., J Biol Chem. 2012 Jun 15;287(25):21416-28. Epub 2012 Apr 30.Fig 10.; doi: 10.1074/jbc.M111.328278; June 15, 2012, The Journal of Biological Chemistry, 287, 21416-21428.

Anti-Kv beta 1 antibody [S40-17] (ab99012) 使用論文

This product has been referenced in:
  • David M  et al. Protein Kinase C (PKC) Activity Regulates Functional Effects of Kvß1.3 Subunit on KV1.5 Channels: IDENTIFICATION OF A CARDIAC Kv1.5 CHANNELOSOME. J Biol Chem 287:21416-28 (2012). WB ; Human . Read more (PubMed: 22547057) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"